Case: Jayden from Trinidad and Tobago

Nationality：

Trinidad and Tobago

Age：

4 years old

Diagnosis：

Cerebral Palsy

Admission Date：

Nov 2014

Background

Jayden (4yo), full-term SVD with no perinatal hypoxia. Day 5: Neonatal jaundice (bilirubin 39μmol/L) → transfusion-associated coma → spontaneous awakening with absent audiovisual responses.

At 2mo: Diagnosed pyloric stenosis (surgical correction) → partial feeding tolerance (pureed/semi-liquid diets). Rehab initiated then abandoned.

Pre-Treatment Condition (Before the First Course of Treatment)

1. Expressive-receptive language disorder: Single words only;
2. Bilateral upper limb contractures: Hand fisting + elbow flexion;
3. Gross motor delay: GMFCS Level V (non-ambulatory);
4. Spastic diplegia: Modified Ashworth Scale 3 (LL);
5. Gait pathology: Scissoring + toe-walking (assisted mobility);
6. Feeding impairment: FOIS Level 4 (pureed/semi-liquid).

Treatment Plan

Two weeks of stem cell therapy
Surgical method: Lumbar puncture and Stereotactic brain surgery
Efficacy monitoring plan over 6 to 12 months post-treatment

After the First Course of Treatment(12 months)

1. Speech & Language Development: can produces complex phrases; measurable improvement in comprehension;
2. Upper Limb Function: achieves full hand extension; reduction in elbow flexor hypertonia;
3. Gross Motor Milestones: independent sitting for 10 minutes; independent standing for 3 minutes;
4. Gait & Lower Limb Function: consistent heel strike pattern during assisted ambulation; marked reduction in scissoring.

Symptom	Improvement
Expressive-receptive language disorder	Multi-phrase communication
Bilateral upper limb contractures (Ashworth 3)	Full hand extension + reduced flexor tone
GMFCS Level V (non-ambulatory)	Independent sitting/standing
Scissoring gait (Wisconsin Gait Scale 18/24)	Heel strike pattern
Bilateral hand rotation discoordination	Improved bimanual coordination
Left hand rigidity (finger tasks)	Enhanced digital dexterity (precision grip)

Progress Summary & Future Outlook

Based on the significant progress made after the first course of stem cell treatment, there is great hope for continued improvement. With a comprehensive approach that combines medical interventions, rehabilitation therapies, and continuous monitoring, the child has the potential to overcome many of their current limitations and lead a more normal, fulfilling life.