Stroke, also known as a cerebrovascular accident, is a serious medical condition that occurs when the brain's blood flow is suddenly blocked or ruptured, resulting in damage to brain tissue. Depending on which part of the brain is affected, patients may experience symptoms such as sudden limb weakness or paralysis, slurred speech, facial drooping, vision problems, or loss of balance. Beyond these physical impairments, stroke often causes long-term complications like cognitive decline, emotional instability, and difficulty performing daily activities, which can greatly affect both the patient's independence and quality of life.
Stroke can be broadly categorized into two main types based on the underlying cause of the interruption in blood flow to the brain: ischemic stroke and hemorrhagic stroke. A third category, transient ischemic attack (TIA), is often referred to as a "mini-stroke" but serves as an important warning sign of future stroke risk.
Ischemic stroke accounts for approximately 80–85% of all stroke cases. It occurs when a blood clot or atherosclerotic plaque blocks an artery supplying the brain, cutting off oxygen and nutrients to brain tissue. Without prompt restoration of blood flow, neurons in the affected area begin to die within minutes. Stem cell transplantation for ischemic stroke is being actively explored as a potential therapy to promote neuronal repair, angiogenesis, and functional recovery in these patients.
Hemorrhagic stroke occurs when a weakened blood vessel ruptures, leading to bleeding within or around the brain. This type of stroke is commonly caused by hypertension, aneurysm rupture, or vascular malformations. The leaked blood increases intracranial pressure and damages surrounding tissue. Emerging research suggests that stem cells for hemorrhagic stroke may help control inflammation, support tissue repair, and enhance neurological recovery following bleeding events.
Often called a "mini-stroke", a transient ischemic attack is a temporary blockage of blood flow to the brain that lasts only a few minutes and causes no permanent damage. However, a TIA serves as a critical warning sign, as many individuals experience a major stroke within days or weeks after a TIA. Early intervention and preventive care are therefore essential.
For many stroke survivors, the most difficult part begins after the emergency has passed—regaining movement, speech, and independence. Conventional rehabilitation can help manage symptoms, but it often cannot repair the brain tissue that was lost during the stroke. This is where stem cell therapy for stroke patients offers a breakthrough in modern regenerative medicine.
Unlike traditional treatments, stem cells for stroke target the root cause of neurological damage by restoring and regenerating the brain's cellular structure. Through multiple biological mechanisms, stem cells work to heal the injured brain and improve functional recovery:
Stem cells have the remarkable ability to transform into neurons, astrocytes, and oligodendrocytes—replacing the brain cells destroyed by a stroke. This process rebuilds disrupted neural pathways, helping patients regain motor skills, coordination, and speech function.
During an ischemic stroke, restricted blood flow deprives the brain of oxygen. Stem cell transplantation for ischemic stroke stimulates angiogenesis by releasing vascular endothelial growth factor (VEGF), promoting the formation of new blood vessels and enhancing oxygen delivery to damaged regions.
After a stroke, inflammation can worsen neural damage. Mesenchymal stem cells modulate immune responses and suppress inflammatory cytokines such as TNF-α and IL-6, protecting remaining brain tissue and reducing secondary damage. This effect is particularly beneficial for stem cells for hemorrhagic stroke, where controlling inflammation is vital for recovery.
Stem cells secrete neurotrophic factors like brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), which nourish surviving neurons and enhance synaptic remodeling. These mechanisms facilitate stem cell for stroke rehabilitation, helping patients regain cognitive function and quality of life.
Before introducing clinical applications, our team conducted years of preclinical research using advanced animal models. From optimizing stem cell transplantation for ischemic stroke techniques to refining the extraction and differentiation of neural stem cells, we built a solid scientific foundation ensuring both the safety and efficacy of our treatments. These findings provide robust support for clinical success and innovation in stem cells for stroke therapy.
Since performing our first stem cell therapy for stroke victim in 2002, SunMoon has remained at the forefront of clinical innovation. We have successfully treated diverse cases—from conventional strokes to complex causes such as lupus-related and moyamoya disease-induced strokes. With precise evaluation and risk assessment systems, we ensure every patient receives tailored and reliable care. Our consistent treatment outcomes have positioned SunMoon as a trusted leader in stem cell therapy for stroke in China and worldwide.
SunMoon adopts a multidisciplinary approach, integrating modern regenerative techniques with traditional rehabilitation and pharmacological therapies. Each patient receives a customized stem cell for stroke recovery plan, designed according to their physical condition and recovery goals. Our dedicated team also provides long-term follow-up and rehabilitation support, ensuring sustained improvement in brain function and quality of life.
By the end of 2024, SunMoon has successfully treated 2,097 stroke patients, including those affected by cerebral hemorrhage and cerebral thrombosis.
Patients' conditions ranged from 1 month to 19 years post-stroke, reflecting SunMoon's expertise in managing both acute and chronic stroke sequelae.
Ongoing studies on stem cell transplantation for ischemic stroke and other cerebrovascular disorders explore its effectiveness during acute and recovery phases.
Early intervention with stem cell therapy for stroke patients protects neurons in the ischemic penumbra, restoring their function and preventing permanent damage.
Clinical findings demonstrate that stem cells for stroke can significantly decrease disability severity and promote neurological recovery.
Delayed treatment allows neuronal degeneration and glial scar formation, increasing complexity. Hence, early medical attention is essential for optimal outcomes.
| Improvement Area | Observed Results |
| Motor Function | Increased muscle strength, better balance, improved gait; some patients regained independent walking ability. |
| Language Ability | Clearer pronunciation, enhanced comprehension and expression in aphasia or dysarthria cases. |
| Sensory Function | Reduced numbness, improved tactile and temperature sensation on affected areas. |
| Cognitive Function | Enhanced memory, attention, and executive function — key outcomes of stem cell for stroke recovery. |
| Swallowing Function | Easier swallowing, lowered aspiration risk, improved feeding safety. |
| Emotional Well-being | Noticeable relief from depression and anxiety; better mood stability and adaptability. |
| Daily Living Activities | Improved ability to eat, dress, and manage personal care independently, supporting long-term stroke rehabilitation. |
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Recent advances in stroke management extend beyond conventional rehabilitation and medication. Among the most promising innovations is stem cell therapy for stroke patients, which aims to repair damaged neural tissue and restore neurological function. This regenerative approach focuses on replacing lost or injured brain cells and promoting natural healing through stem cell transplantation for ischemic and hemorrhagic stroke.
Yes. Stem cells for stroke recovery have shown the potential to regenerate neurons and support the brain's self-repair mechanisms. When transplanted, stem cells may release growth factors that stimulate neurogenesis, angiogenesis, and synaptic reconnection, helping restore functions impaired by stroke. While research is ongoing, clinical data increasingly support stem cell therapy for stroke victims as a viable method to enhance recovery outcomes.
Clinical studies indicate that stem cell therapy for stroke rehabilitation can significantly improve motor function, speech, and cognitive abilities in selected patients. The degree of improvement depends on factors such as the type of stroke (ischemic or hemorrhagic), timing of treatment, and overall health condition. Many patients receiving stem cell transplantation for ischemic stroke report enhanced physical coordination and reduced disability compared with traditional therapy alone.
Recovery after a stroke varies widely. In general, the brain begins its repair process within weeks, but complete rehabilitation can take months or even years. Incorporating stem cells for stroke recovery into the treatment plan may accelerate healing by promoting neuronal regeneration and improving vascular function. Early intervention and consistent rehabilitation remain critical for optimal recovery outcomes.
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