Osteoarthritis-Case-Wang-Ziyuan

Ms. Jiang from China

Nationality：China

Age: 38 years old

Diagnosis : Osteoarthritis

Admission Date：Mar 2009

Background

Ms. Jiang is from Jiangxi Province of China. In Oct 2008, her knee joint swelled, she felt numbness of the muscle, fatigue and pain for both knees, but she didn't go for treatment. Then the conditions worsened, pain for both knees, she had difficulties to walk and squat for 6 months. Therefore she was recommended to our hospital for further treatment in Mar 2009. The diagnosis is osteoarthritis for both knees.

Pre-Treatment Condition（Before Stem Cell Treatment）

1. Physical examination result: Tenderness(+) of structures surrounding the affected joints;joints deformity.
2. Left knee's maximum flexion is 80°and extension is 10°; right knee's maximum flexion is 100°and extension is 15°; squatting was affected obviously.
3. X-ray test result: Remarkable osteoproliferation of the surrounding margin of bilateral patella; tibial plateau and intercondylar eminence.
4. Calcification of ligament: Cartilage on articular surface worn, partially fell off, margin narrowed with unequal width.

Treatment Plan

One course of stem cell therapy
Surgical method: Intra-articular Treatment
Efficacy monitoring plan over 6 to 12 months post-treatment

After the First Course ofTreatment (6 months)

Bilateral knee pain and fatigue disappeared;
Normal squatting without difficulty, normal gait.
Tenderness of surrounding structures of bilateral knees disappeared.
Left knee flexion 140°, extension 20°, right knee flexion 145°, extension 20°.
Be able to move around as normal, she's independent in daily activities.

Category	Symptom	Improvement
Joint Symptoms	Tenderness (+), joint deformity.	Pain/fatigue resolved; no tenderness.
Range of Motion	Left knee: 80° flexion/10° extension Right knee: 100° flexion/15° extension.	Left knee: 140° flexion/20° extension Right knee: 145° flexion/20° extension.
Imaging Findings	Severely limited squatting; impaired gait.	Normal squatting, gait, and independent daily activities.

Progress Summary & Future Outlook

Looking ahead, Ms. Jiang's remarkable recovery from osteoarthritis of both knees after the first course of stem cell treatment gives us great hope. With her current improved condition, she can expect to maintain an active lifestyle in the long run. We anticipate that continued follow-up care and potential further treatments, if necessary, will ensure the long-term stability of her knee joints. She may engage in more physical activities, enjoy a higher quality of life, and be free from the limitations that once plagued her.