The infant was delivered full-term via uncomplicated vaginal birth, with no history of perinatal asphyxia or hypoxia. At five days old, he was diagnosed with neonatal jaundice (serum bilirubin: 39 μmol/L), despite no family history of genetic disorders. Following a blood transfusion, he unexpectedly developed a coma of unknown etiology and required nutritional support. After 5-6 days, he spontaneously regained consciousness but exhibited no responsiveness to auditory or visual stimuli.  

At two months of age, the infant presented with persistent feeding difficulties, leading to a diagnosis of pyloric stenosis (a gastric outflow obstruction) at a local hospital. He underwent pyloromyotomy (corrective surgery), after which feeding improved marginally, though intake remained restricted to pureed and semi-liquid foods. Rehabilitation therapy was initiated but later discontinued and has not been resumed to date.  

Pre-Treatment Condition (Before the First Course of Treatment)

1. Speech & Language: utters simple words/phrases; demonstrates severely impaired receptive language skills.  

2. Upper Limb Function: persistent bilateral hand fisting; fixed elbow flexion contractures.

3. Gross Motor Skills: unable to achieve independent sitting, standing, or ambulation

4. Neuromuscular Status: hypertonia in lower extremities 

5. Gait Abnormalities: scissoring gait and bilateral toe-walking, requiring parental support for ambulation.  

6. Nutritional Status: persistently reduced oral intake/appetite.

Pre-Treatment Condition (Before the First Course of Treatment)