Case: Wang Le
Nationality:
China
Age:
6 Years old
Diagnosis:
Autism
First Admission Date:
July 2010
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Background

Patient was born in full-term caesarean section, no asphyxia after birth, good general condition. Facial skin stained yellow occurred in the second day of birth and lasted 45 days until it got better without any specific treatment. Since then the parents found out that the patient’s growth is slower than her peers, she could not sit independently until 7 months, could not climb until 9 months, could not stand independently when turned 1 year old, so she went to the PLA General Hospital and was diagnosed as “growth retardation”, was given gangliosides treatment (the specific medicine and dosage are unknown) for 10 months, patient could stand on her own then. When turned 2, patient could walk independently, but not steadily. She could not speak simple words and polyphonic words until 2 years old, but the patient could suddenly say several sentences and fully recite children’s songs after turned 2. In December, 2008, patient attended to Peking University Sixth Hospital, her autism behavior checklist got 56 points, was considered as autism and didn't receive any specific treatment. Then she attended to An'ding Hospital in April, 2009, was given risperidone treatment (unknown dosage and administration ) but did not see any improvement. Since then patient stayed home and has been treated by acupuncture and functional rehabilitation exercises, until she came to our hospital for stem cell transplantation to expect further treatment. Since the onset of disease, the patient has normal mentality,good appetite, normal stool and urine.

Patient was admitted to hospital for main complaint of “speech and mental developmental delay for more than 3 years” in July 2nd, 2010.

Pre-Treatment Condition (Before the First Course of Treatment)


•  Mental retardation, hyperactivity, short-tempered.

•  Can speak simple words, hyperactive, do not communicate with others.

•  Good memory, calculation ability, comprehension and orientation, do not cooperate the physical examination.

•  Soft neck, no resistance, negative to Klinefelter's syndrome.

First Course of  Stem Cell Treatment  (July 2010)

Treatment Methods:
lumbar puncture+IV Injection

Outcomes After the First Course of Treatment


•  Much less hyperactive than before, better in concentrating, learning, understanding and receptiveness.

•  Patient can communicate with her parents, and will follow their instructions.

•  Considerable improvements of intelligence, and better ability to accept new things.

•  Her temper become much better than before.

Progress Summary & Future Outlook

With the encouraging results from the first stem cell treatment, the future holds great promise. As time passes, further treatments or natural development could lead to even more profound changes. 

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