In April 2015, the patient had symptoms of dry mouth, polydipsia, polyuria, and polyphagia without precipitating factor. He didn't pay much attention until 1 month later, above symptoms were still existing and deteriorated. His water intake reached to 3000ml, and he got fatigue much easier than before. He came to General Hospital of Chinese People’s Armed Police Forces for treatment in May. His main medical examinations show: Fasting glucose 16.48mmol/L, 2-hour postprandial blood glucose 28.16 mmol/L; urine: urine sugar (+), ketones (-), glycosylated hemoglobin 9.0%.]
Pre-Treatment Condition (Before the First Course of Treatment)
• Alarming Symptom Manifestations
The patient has been grappling with a trio of distressing symptoms. Intense thirst has become a constant companion, leaving him perpetually parched. This unquenchable thirst has led to polydipsia, causing him to consume fluids in excessive amounts throughout the day. Simultaneously, he has experienced a significant and concerning weight loss. Without any intentional dietary changes or increased physical activity, his body weight has been steadily dropping, leaving him visibly thinner and more frail.
• Abnormal Blood Indices
The patient's fasting blood glucose index is strikingly elevated, far exceeding the normal range. Measuring up to 15.6mmol/L, this high value indicates a severe disruption in his body's blood sugar - regulating mechanisms. Similarly, the glycated hemoglobin index, which reflects average blood sugar levels over an extended period, is also alarmingly high at 10.6%. Such elevated levels are clear signs of a long - standing and poorly controlled blood sugar issue, pointing strongly towards a diagnosis of diabetes.
• Persistent Fatigue
Weakness has become a near - constant state for the patient. He frequently feels a profound lack of energy, making even the most basic daily tasks a struggle. Simple activities like climbing a flight of stairs, getting up from a chair, or walking a short distance can leave him breathless and exhausted. This persistent fatigue not only impacts his physical capabilities but also takes a toll on his mental well-being, leading to feelings of frustration and helplessness.
First Course of Stem Cell Treatment (Jan 2012 )
Outcomes After the First Course of Treatment
• Symptom Alleviation
The patient has experienced a remarkable relief in several key symptoms. Dry mouth, which once caused discomfort and a constant need for sips of water, has become a thing of the past. Polydipsia, the excessive thirst that drove him to consume large volumes of fluids, has subsided significantly. Polyuria, the frequent urge to urinate, is no longer disrupting his daily routine, and polyphagia, the insatiable hunger, has also been curbed.
• Weight Gain and Well - being
A notable physical change is the 3-kg weight gain. This increase in weight is a positive sign, indicating that his body's metabolism is stabilizing. Along with the weight gain, his physical and mental condition has improved dramatically. He has more energy to engage in daily activities, whether it's household chores or going for a walk.
• Blood Glucose and Glycated Hemoglobin Control
The patient's blood glucose levels are now well-managed. Fasting blood glucose generally stays within the range of 5 - 8 mmol/L, which is close to the normal level. The 2 - hour postprandial blood glucose, an important indicator of how the body processes food, is maintained within 8 - 11mmol/L. Additionally, his glycated hemoglobin, a long - term marker of blood sugar control, is successfully controlled at 6.5%, which is within the target range for good diabetes management. Moreover, the urine sugar test shows a negative result, further confirming the effectiveness of the treatment.
Progress Summary & Future Outlook
The patient's current progress is highly encouraging, laying a solid foundation for a promising future. With symptoms alleviated and blood sugar well-controlled, they can look forward to a more active lifestyle. The improved physical and mental state allows for regular exercise, like jogging or cycling, which will further boost health. As time goes on, continued proper management might even lead to better long - term blood sugar stability, potentially reducing the risk of diabetes - related complications. They'll likely integrate fully into social and work life, enjoying a life free from the prior limitations and worries brought on by the illness.
