Case: Mr Cao
Nationality:
China
Age:
36 years old
Diagnosis:
Diabetes
First Admission Date:
Oct 2016
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Background


Since the beginning of 2014, the patient has developed symptoms such as dry mouth, polydipsia, polyuria, significant weight loss, and weakness of limbs. He has not controlled diet and loves sweets on weekdays, and does not pay attention to exercise. In September 2016, the patient had blurred vision of both eyes, the left eye had a significant decrease in visual acuity, and the right eye had good visual acuity. He was treated at a local hospital and combined with the results and symptoms to diagnose diabetes.

Pre-Treatment Condition (Before the First Course of Treatment)


• He suffered from dry mouth, polydipsia, polyuria, obviously reduced weight etc. without obvious incentive since the beginning of 2007, while he did not pay attention to it, he did not control his diet and he loved to eat sweet foods without necessary sports;

• He suffered from blurred visions of both eyes, the left vision reduced obviously, the right vision was ok; the fasting blood glucose: 17.48mmol/L; the blood glucose of 2 hours after the meal: 25.0 mmol/L; glycosycated hemoglobin: 7.8%; fasting C peptite: 745.7 pmmol/L(250-600); the urine micro protein showed negative; eye ground showed there was spot, strip, splinter hemorrhage, hard and cotton effusion on both eyes ground, which was diagnosed as type II diabetes with VI phase diabetic retinas disease;

• He was given insulin to reduce the blood glucose, the blood glucose level is controlled well and stably, his symptoms of dry mouth, polyuria, polydipsia were relieved obviously;

• He was offered laser treatment for his both eyes ground on September 30th, 2010 while his blurred visions could not be improved obviously after the operation, the visions of his both eyes are all 0.3.

• He received a round stem cell treatment in our hospital on October 13th, 2010. After his admission, he received anti-diabetes treatment including Novolin 30R 15iu via hypodermic injection 30 minutes before every breakfast and dinner; diformin tablets 0.5g by oral administration 3 times/day; Acarbose tablets 100mg by oral administration 3 times/day.

First Course of  Stem Cell Treatment  (Jan 2012 )

Treatment Methods:
Interventional therapy + intravenous injection 

Outcomes After the First Course of Treatment (1 month)


• Symptoms Remission: Symptoms like dry mouth, polydipsia, polyuria, and polyphagia vanished.

• Weight Increase: His weight rose by 2 kg.

• Medication Adjustment: He discontinued oral anti - diabetes meds, and insulin injection dosage decreased from 30iu/day to 20iu/day.

• Blood Indices: Blood glucose was stable, and glycosylated hemoglobin dropped significantly.

• Vision Improvement: Vision improved from 0.3 to 0.5, enabling him to see surroundings clearly.

Outcomes After the First Course of Treatment (3 months)

• Complete Symptom Resolution: All symptoms of dry mouth, polydipsia, polyuria, and polyphagia disappeared entirely.

• Stable Weight: His weight remained the same as the last measurement.

• Further Medication Reduction: Oral meds stayed stopped, and insulin injection dosage was cut to 12iu/day.

• Normal Blood Indices: Blood glucose, glycosylated hemoglobin, and blood lipid levels were normal.

• Vision Enhancement: Vision in both eyes increased to 0.6, with clear vision of surrounding objects.

• Life Quality Upgrade: He could drive independently, indicating a marked improvement in life quality.

Outcomes After the First Course of Treatment (6 months)


• Permanent Symptom Relief: Symptoms were completely gone, and his weight was stable.

• Medication Cessation: He stopped all anti - diabetes meds and insulin injections.

• Normal Blood Parameters: Both glycosylated hemoglobin and blood glucose levels were normal.

• Stable Vision: Vision in both eyes stably remained at 0.6.

Progress Summary & Future Outlook

Given his current progress, the future holds promise. With the stem cell treatment and ongoing anti-diabetes therapy, his blood glucose may remain stably normal, allowing him to completely halt insulin and oral medications. His vision could potentially improve further, enabling him to drive more confidently and engage in activities that were once challenging. He may be able to return to a normal diet, with proper moderation, and resume an active lifestyle. This new lease on life will not only enhance his physical health but also significantly boost his mental well - being and social interactions.             



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